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Marta Zarandi Selected Research

Har(29)- Arg(28) Nle(27) Orn(21) His(20) Orn(12,) Abu(15) His(11) Tyr(Me)(10) Har(9) Ala(8) Fpa(5,6) Arg(2) (PhAc-Ada)(0)-Tyr(1) GHRH(1-29)NH2

1/2017Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth.
1/2014Preclinical efficacy of growth hormone-releasing hormone antagonists for androgen-dependent and castration-resistant human prostate cancer.
1/2014Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function.
2/2012Novel antagonists of growth hormone-releasing hormone inhibit growth and vascularization of human experimental ovarian cancers.
10/2011The effect of a novel antagonist of growth hormone releasing hormone on cell proliferation and on the key cell signaling pathways in nine different breast cancer cell lines.
11/2010The effect of GHRH antagonists on human glioblastomas and their mechanism of action.

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Marta Zarandi Research Topics

Disease

31Neoplasms (Cancer)
01/2017 - 02/2004
12Prostatic Neoplasms (Prostate Cancer)
01/2017 - 01/2005
5Glioblastoma (Glioblastoma Multiforme)
01/2014 - 11/2005
4Lymphoma (Lymphomas)
01/2017 - 10/2004
3Neoplasm Metastasis (Metastasis)
12/2013 - 01/2005
3Ovarian Neoplasms (Ovarian Cancer)
02/2012 - 05/2010
2Adenocarcinoma
01/2017 - 02/2012
2Myocardial Infarction
01/2015 - 02/2014
2Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
04/2012 - 03/2011
2Breast Neoplasms (Breast Cancer)
10/2011 - 11/2008
2Endometrial Neoplasms (Endometrial Cancer)
12/2010 - 06/2005
2Pancreatic Neoplasms (Pancreatic Cancer)
03/2006 - 11/2005
2Carcinoma (Carcinomatosis)
11/2005 - 01/2005
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
08/2005 - 11/2004
1Renal Cell Carcinoma (Grawitz Tumor)
01/2017
1Wounds and Injuries (Trauma)
01/2016
1Heart Failure
01/2015
1Melanoma (Melanoma, Malignant)
01/2014
1Lower Urinary Tract Symptoms
04/2012
1Adenoma (Adenomas)
01/2012
1Acromegaly
01/2012
1Triple Negative Breast Neoplasms
10/2011
1Colonic Neoplasms (Colon Cancer)
10/2009
1Colorectal Neoplasms (Colorectal Cancer)
07/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2007
1Lung Neoplasms (Lung Cancer)
11/2005
1Spontaneous Fractures (Pathological Fracture)
01/2005

Drug/Important Bio-Agent (IBA)

29Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
01/2015 - 10/2004
14somatotropin releasing hormone receptorIBA
01/2017 - 10/2004
10AndrogensIBA
01/2014 - 01/2005
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2013 - 06/2005
6Har(29)- Arg(28) Nle(27) Orn(21) His(20) Orn(12,) Abu(15) His(11) Tyr(Me)(10) Har(9) Ala(8) Fpa(5,6) Arg(2) (PhAc-Ada)(0)-Tyr(1) GHRH(1-29)NH2IBA
01/2017 - 11/2010
6PhAcTyr(1)- Arg(2)- P(H)e(4- CL)(6)- Ala(8)- Tyr(Me)(10)- His(11)- Abu(15)- His(20)- Nle(27)- Arg(28)- HLCr(29)- GHRH(1-29)NH2IBA
04/2012 - 11/2008
6MZ-J-7-118IBA
09/2007 - 01/2005
6BombesinIBA
04/2007 - 11/2004
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2013 - 08/2005
5Hca(6)-Leu(13)-psi(CH2N)-Tac(14)- bombesin(6-14)IBA
04/2007 - 11/2004
5Gastrin-Releasing PeptideIBA
04/2007 - 11/2004
4Hormones (Hormone)IBA
01/2017 - 10/2004
4Proteins (Proteins, Gene)FDA Link
04/2012 - 11/2005
4MZ-J-7-138IBA
04/2012 - 07/2005
4Messenger RNA (mRNA)IBA
11/2005 - 06/2005
3Gonadotropin-Releasing Hormone (GnRH)FDA Link
04/2012 - 09/2007
3cetrorelix (Cetrotide)FDA Link
04/2012 - 09/2007
3LigandsIBA
02/2012 - 10/2004
3Peptides (Polypeptides)IBA
01/2012 - 03/2005
3Estrogens (Estrogen)FDA Link
10/2011 - 11/2008
3ErbB Receptors (EGF Receptor)IBA
05/2010 - 08/2005
3Insulin-Like Growth Factor II (Somatomedin A)IBA
12/2008 - 06/2005
3Epidermal Growth Factor (EGF)IBA
09/2007 - 08/2005
3Insulin-Like Growth Factor I (IGF-1)IBA
03/2006 - 07/2005
2Human Growth Hormone (Saizen)FDA LinkGeneric
01/2017 - 10/2004
2N-Me-Tyr1,D-Ala2,Asn8,Arg29-NHCH3-JI-38IBA
01/2016 - 02/2014
2MIA-690IBA
01/2014 - 01/2014
2matrigelIBA
02/2012 - 07/2010
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
02/2012 - 04/2007
2JV 1-36IBA
01/2012 - 03/2006
2JV 1-38IBA
03/2006 - 03/2005
2Protein Isoforms (Isoforms)IBA
11/2004 - 10/2004
1MR 356IBA
02/2014
1JI-38IBA
02/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2014
1Pharmaceutical PreparationsIBA
01/2014
1Dihydrotachysterol (AT 10)IBA
01/2014
1S100 Calcium-Binding Protein A4IBA
12/2013
1CD146 AntigenIBA
12/2013
1SynucleinsIBA
12/2013
1Metalloproteases (Metalloproteinases)IBA
12/2013
1Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)IBA
12/2013
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
12/2013
1Tumor Biomarkers (Tumor Markers)IBA
12/2013
1NeuropeptidesIBA
04/2012
1Testosterone (Sustanon)FDA Link
04/2012
1ImmunosorbentsIBA
02/2012
1EnzymesIBA
02/2012
1TOR Serine-Threonine KinasesIBA
01/2012
1Phosphotransferases (Kinase)IBA
01/2012
1vapreotideIBA
01/2012
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2012
1MZ 4-71IBA
01/2012
1ProgesteroneFDA LinkGeneric
10/2011
1endonuclease GIBA
11/2010
1Apoptosis Inducing FactorIBA
11/2010
1Cytochromes c (Cytochrome c)IBA
11/2010
1Fibronectins (Fibronectin)IBA
07/2010
1ParaffinIBA
07/2009
1Calcibiotic Root Canal SealerIBA
07/2009
1Estrogen ReceptorsIBA
11/2008
1CarbonIBA
03/2006
1Fatty Acids (Saturated Fatty Acids)IBA
03/2006
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
08/2005
1MZ 5-156IBA
07/2005
1Protein Kinase CIBA
11/2004
1Immune Sera (Antisera)IBA
10/2004
1Insulin-Like PeptidesIBA
02/2004

Therapy/Procedure

12Therapeutics
01/2014 - 01/2005
3Castration
01/2014 - 09/2007
1Drug Therapy (Chemotherapy)
01/2014
1Aftercare (After-Treatment)
11/2010